A meta-analysis of genome-wide association studies identifies multiple longevity genes

“We performed a genome-wide association study of longevity-related phenotypes in individuals of European, East Asian and African American ancestry and identified the APOE and GPR78 loci to be associated with these phenotypes in our study. Moreover, our gene-level association analyses highlight a role for tissue-specific expression of genes at chromosome 5q13.3, 12q13.2, 17q21.31, and 19q13.32 […]

Longevity and anti-aging research: ‘Prime time for an impact on the globe’

David Sinclair is among a group of researchers collaborating on a new nonprofit academy to promote aging research and drug discovery. “We’re generally in denial that, for most of the diseases that we get these days, the root cause is aging. I don’t know 10-year-olds that get Alzheimer’s disease or heart disease.”- David Sinclair The […]

‘Tickle’ therapy could help slow aging, research suggests

‘Tickling’ the ear with a small electrical current appears to rebalance the autonomic nervous system for over-55s, potentially slowing down one of the effects of ageing, according to new research at the University of Leeds. The new study explores the impact the vagus nerve has on age.  The therapy, called transcutaneous vagus nerve stimulation, delivers […]

Do you LOVE your heart as much as it loves you?

What causes high blood pressure and what can you do to avoid it happening to you. The next time you are waiting in line at the Department of Motor Vehicles, look around. The probability is good that one-in-three people, sitting, standing, taking a number or complaining at customer service, suffer from high blood pressure. According […]

How stopping cell death may help prevent rheumatoid arthritis

Research in mice now shows that a specific cell death mechanism can lead to rheumatoid arthritis. Stopping this mechanism could help prevent this condition from developing, the authors argue. Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized mainly by pain and stiffness in the joints due to inflammation in the joint lining. Some of […]

Can social interaction predict cognitive decline?

Overall, the authors found no relationship between social interaction and cognitive decline. However, when they delved into the beta-amyloid data, a pattern formed. The researchers found that the influence of social activity was significant in individuals who had the highest levels of beta-amyloid in their brains. In this group, those with the lowest levels of […]

How Does Exercise Support Health Later in Life?

Insufficient physical activity causes around 3.2 million deaths worldwide each year, according to the World Health Organization (WHO). These declining levels of physical activity may be due, in part, to an increase in sedentary behavior, heavy traffic areas, pollution, and a lack of parks and facilities. For adults aged 65 and above, experts define physical […]

Do you have annuity with your immunity?

Take this Immunity Test to check you are doing everything you can to keep your immune system strong. Our immune system is the gate keeper, without it, the human body could not survive on earth, with its biological environment filled with foreign invaders, parasites, bacteria and multitudes of viruses. On any given day, our system […]

Why NAD+ Declines during Aging: It’s Destroyed

NAD+ is required not only for life but for a long life. Implicated is the decline of NAD+ during aging, and for combating age-related diseases. NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme existing in all cells but latest research is proving NAD+ declines during the aging process to nil in our very late years. Although […]