How stopping cell death may help prevent rheumatoid arthritis

Research in mice now shows that a specific cell death mechanism can lead to rheumatoid arthritis. Stopping this mechanism could help prevent this condition from developing, the authors argue.

Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized mainly by pain and stiffness in the joints due to inflammation in the joint lining.

Some of the main risk factors for RA are age (people over 60 are more at risk), sex (this condition is more common in women), and the expression of specific genes. According to the Arthritis Foundation, around 54 million adults in the United States have a diagnosis of arthritis. Other data indicate that RA affects approximately 1% of the world’s population.

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